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KMID : 0356720060220050346
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Journal of the Korean Society of Coloproctology
2006 Volume.22 No. 5 p.346 ~ p.349
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Sigmoid Colon Cancer with Isolated Metastasis to the Left Kidney
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Kim Hyung Jin
Choi Ho-Joong
Kang Won-Kyung
Oh Soon-Nam
Jung Chan-Kwon
Oh Seung-Tack
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Abstract
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We report the case of a 63-year-old female with sigmoid colon cancer and isolated metastasis to the left kidney at the time of initial diagnosis. An anterior resection of the sigmoid colon and a left nephrectomy were performed. Three cycles of adjuvant chemotherapy consisting of oxaliplatin, 5-fluorouracil, and leucovorin were given, but two months after the surgery, multiple metastases of the liver were detected on a CT scan. The patient refused further treatment and died 5 months after the discovery of an isolated metastasis. An isolated metastasis to the kidney is very rare in clinical practice. A nephrectomy for kidney metastasis has no effect on survival and quality of life, and a nephrectomy may also compromise the choice of chemotherapy agents that require renal clearance; thus, a careful evaluation of renal function is necessary before a nephrectomy. At present, kidney metastasis should be regarded as an advanced metastatic disease, and aggressive chemotherapy, including target therapy, should prolong survival and improve the quality of life. However, when a synchronous or a metachronous renal tumor is suspected, a nephrectomy should be performed for accurate diagnosis and treatment. J Korean Soc Coloproctol 2006;22:346- 349
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KEYWORD
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Sigmoid colon cancer, Kidney metastasis, Nephrectomy, Synchronous cancer
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